Month: March 2019

The first antidepressant had a tricyclic chemical structure (imipramine) and was discovered by chance in the 50s of the twentieth century – in the search for drugs for the treatment of schizophrenia. Tricyclic antidepressants (TCAs)

The pharmacological action of antidepressants is due to the following mechanisms: delayed recovery of norepinephrine, serotonin, and dopamine; sodium antagonistic effects; blockade of muscarinic acetylcholine receptors; histamine (HI) receptor block, alpha-1 receptor blockade, serotonin-2 (5-HT2)

Side effects of therapy, especially gastrointestinal (nausea, vomiting, flatulence, etc.), cardiac (heartbeat, arrhythmias, orthostatic hypotension, etc.), neurological (headache, tremor, sweating, etc.) endocrinological (weight gain, changes in menstruation cycle, etc.), manifestations sexual dysfunction Reducing the quality

The most important role in the medical treatment of depression is played by antidepressants – drugs that systematically improve the patient’s condition, relieve symptoms of depression: emotional disorders, motor and cognitive impairments (memory, attention, thinking),

Biological treatment of depression, in the first place, includes pharmacological therapy. At the same time, for the biological treatment of depressive spectrum disorders, electroconvulsive therapy, sleep deprivation, phototherapy, diet therapy, herbal therapy, efferent sorption techniques,

Unfortunately, most people suffering from depression are not aware that they are sick and, therefore, do not consider it necessary to seek medical help. In addition, many patients are convinced that it is impossible to

The question of the differential diagnosis of disorders of the depressive spectrum is quite complex. Here, the positions of researchers have been repeatedly revised both in connection with the change in ideas about depression, and

Of interest are instrumental methods for diagnosing depression. The use of computed tomography was limited due to the low resolution and artifacts created by the bones of the skull. In some studies, ventricular enlargement has

The clinical symptoms of postpartum depression lead to the idea that this condition is one of the variants of a “major depressive disorder,” especially since it can last for several months or even years. Postpartum

The group of psychogenic depression also includes depressive reactions in patients with neurological and somatic diseases caused by a number of psychological, social, personal, biological factors, including the objective features of a somatic disease. The