Tricyclic antidepressants

The first antidepressant had a tricyclic chemical structure (imipramine) and was discovered by chance in the 50s of the twentieth century – in the search for drugs for the treatment of schizophrenia. Tricyclic antidepressants (TCAs)

event_note
close

The first antidepressant had a tricyclic chemical structure (imipramine) and was discovered by chance in the 50s of the twentieth century – in the search for drugs for the treatment of schizophrenia. Tricyclic antidepressants (TCAs)

Read more

Pharmacological properties of antidepressants

The pharmacological action of antidepressants is due to the following mechanisms: delayed recovery of norepinephrine, serotonin, and dopamine; sodium antagonistic effects; blockade of muscarinic acetylcholine receptors; histamine (HI) receptor block, alpha-1 receptor blockade, serotonin-2 (5-HT2)

event_note
close

The pharmacological action of antidepressants is due to the following mechanisms: delayed recovery of norepinephrine, serotonin, and dopamine; sodium antagonistic effects; blockade of muscarinic acetylcholine receptors; histamine (HI) receptor block, alpha-1 receptor blockade, serotonin-2 (5-HT2)

Read more

The main reasons for discontinuing antidepressants

Side effects of therapy, especially gastrointestinal (nausea, vomiting, flatulence, etc.), cardiac (heartbeat, arrhythmias, orthostatic hypotension, etc.), neurological (headache, tremor, sweating, etc.) endocrinological (weight gain, changes in menstruation cycle, etc.), manifestations sexual dysfunction Reducing the quality

event_note
close

Side effects of therapy, especially gastrointestinal (nausea, vomiting, flatulence, etc.), cardiac (heartbeat, arrhythmias, orthostatic hypotension, etc.), neurological (headache, tremor, sweating, etc.) endocrinological (weight gain, changes in menstruation cycle, etc.), manifestations sexual dysfunction Reducing the quality

Read more

Antidepressants

The most important role in the medical treatment of depression is played by antidepressants – drugs that systematically improve the patient’s condition, relieve symptoms of depression: emotional disorders, motor and cognitive impairments (memory, attention, thinking),

event_note
close

The most important role in the medical treatment of depression is played by antidepressants – drugs that systematically improve the patient’s condition, relieve symptoms of depression: emotional disorders, motor and cognitive impairments (memory, attention, thinking),

Read more

Biological treatment of depression and pharmacotherapy

Biological treatment of depression, in the first place, includes pharmacological therapy. At the same time, for the biological treatment of depressive spectrum disorders, electroconvulsive therapy, sleep deprivation, phototherapy, diet therapy, herbal therapy, efferent sorption techniques,

event_note
close

Biological treatment of depression, in the first place, includes pharmacological therapy. At the same time, for the biological treatment of depressive spectrum disorders, electroconvulsive therapy, sleep deprivation, phototherapy, diet therapy, herbal therapy, efferent sorption techniques,

Read more

Common Depression Treatment Guidelines

Unfortunately, most people suffering from depression are not aware that they are sick and, therefore, do not consider it necessary to seek medical help. In addition, many patients are convinced that it is impossible to

event_note
close

Unfortunately, most people suffering from depression are not aware that they are sick and, therefore, do not consider it necessary to seek medical help. In addition, many patients are convinced that it is impossible to

Read more

Differential diagnosis of depression

The question of the differential diagnosis of disorders of the depressive spectrum is quite complex. Here, the positions of researchers have been repeatedly revised both in connection with the change in ideas about depression, and

event_note
close

The question of the differential diagnosis of disorders of the depressive spectrum is quite complex. Here, the positions of researchers have been repeatedly revised both in connection with the change in ideas about depression, and

Read more

Instrumental methods for diagnosing depression

Of interest are instrumental methods for diagnosing depression. The use of computed tomography was limited due to the low resolution and artifacts created by the bones of the skull. In some studies, ventricular enlargement has

event_note
close

Of interest are instrumental methods for diagnosing depression. The use of computed tomography was limited due to the low resolution and artifacts created by the bones of the skull. In some studies, ventricular enlargement has

Read more

Postpartum depression

The clinical symptoms of postpartum depression lead to the idea that this condition is one of the variants of a “major depressive disorder,” especially since it can last for several months or even years. Postpartum

event_note
close

The clinical symptoms of postpartum depression lead to the idea that this condition is one of the variants of a “major depressive disorder,” especially since it can last for several months or even years. Postpartum

Read more

Psychogenic depression with somatic and neurological diseases

The group of psychogenic depression also includes depressive reactions in patients with neurological and somatic diseases caused by a number of psychological, social, personal, biological factors, including the objective features of a somatic disease. The

event_note
close

The group of psychogenic depression also includes depressive reactions in patients with neurological and somatic diseases caused by a number of psychological, social, personal, biological factors, including the objective features of a somatic disease. The

Read more